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Dr Mark Osborne
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RSC: Double FRET for Analysis of DNA Mismatch
Reference
Horsey, I., Furey, W. S., Harrison, J. G., Osborne, M. A. & Balasubramanian, S. Double fluorescence resonance energy transfer to explore multicomponent binding interactions: A case study of DNA mismatches. Chem. Commun. 1043–1044 (2000)
A first demonstration, using a four-component system of complementary and single base-mismatched oligonucleotides, that double fluorescence resonance energy transfer (FRET) can be used to interrogate multicomponent interactions in molecular complexes.
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