Dr Mark Osborne
science > ideas > solutions

: a picture book
In 1998, Solexa sequencing emerged at the University of Cambridge from pioneering work of Sir Shankar Balasubramanian and Sir David Klenerman, Dr Colin Barnes and Dr Mark Osborne.
The breakthrough tech revolutionized genomics by paving the way for next-generation sequencing (NGS) of DNA, and the rapid read of life's code that has set the path toward targeted medicine and personalised healthcare...
Back in the day, digital cams were rare/expensive and mobiles were cameraless bricks, so sadly pictures were few, but the collection of notes and visuals below represent a creative spin on the founding years of Solexa from a postdoc, inventor, senior scientist and problem solver perspective...
More on Solexa from the people that were there...
2025 https://medium.com/@nick.mccooke/how-we-pioneered-next-generation-dna-sequencing-at-
2023 https://www.ch.cam.ac.uk/news/researchers-honoured-exceptional-citation-records
2022 https://www.personalis.com/a-celebration-of-solexa-a-short-tour-of-dna-sequencing-history/
2021 https://news.cancerresearchuk.org/2021/10/15/the-award-winning-researcher-behind-next-generation-sequencing/
2016 https://www.enterprise.cam.ac.uk/10th-anniversary-story-solexa/
2017 https://emea.illumina.com/company/news-center/feature-articles/video--solexa-anniversary.html
2010 https://www.bbc.co.uk/programmes/p00bslg4
Other useful links
2024 https://btlj.org/wp-content/uploads/2024/06/0006_39-LSI_Tsai.pdf
2010 https://www.bio-itworld.com/news/2010/09/30/the-solexa-story